Molecule Profile - Facts Document
Name: Bonnie May
Date: September 30, 2014
Date: September 30, 2014
Molecule Selected: Ibuprofen
Why did you choose this molecule? I have to use ibuprofen fairly frequently for pain and headaches, and I want to learn more about what it is and how it works.
How is this molecule important/relevant to your life? It is used as an anti-inflammatory drug often for pain and arthritis. It is very common and many people use it daily for pain. It is important in my life because I need it often.
Facts Source 1
Source 1 Title: 3D Chem: Advil
MLA Citation: Harrison, Karl. "Advil." www.3dchem.com. 3D Chemistry, Dec. 2002. Web.
Facts Source 2
Source 2 Title: Daily Med - Ibuprofen
MLA Citation: "IBUPROFEN - Ibuprofen tablet, Film Coated ." DailyMed. U.S. National Library of Medicine, Mar. 2010. Web.
Why did you choose this molecule? I have to use ibuprofen fairly frequently for pain and headaches, and I want to learn more about what it is and how it works.
How is this molecule important/relevant to your life? It is used as an anti-inflammatory drug often for pain and arthritis. It is very common and many people use it daily for pain. It is important in my life because I need it often.
Facts Source 1
Source 1 Title: 3D Chem: Advil
MLA Citation: Harrison, Karl. "Advil." www.3dchem.com. 3D Chemistry, Dec. 2002. Web.
- Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) which is commonly used for relieving muscular and skeletal pain.
- Ibuprofen is a white powder belonging to the propionic acid derivatives.
- Melting point of 74 - 77° C.
- Its anti-inflammatory, analgesic (pain relieving) and antipyretic (fever reducing) actions, are comparable to those of aspirin and it is commonly taken in tablet form for the relief of mild to moderate pain such as headache, toothache, and migraine as well as symptoms of fever.
- Ibuprofen Tablets are very useful for relief of the signs and symptoms of rheumatoid arthritis and osteoarthritis, to reduce joint swelling and improves the action of joints.
- It is only slightly soluble in water but readily soluble in organic solvents such as ethanol.
- Ibuprofen acts so as to inhibit the action of the enzyme cyclooxygenase, which catalyses the transformation of fatty acids to prostaglandins.
- The synthesis of prostaglandin is inhibited and this is the cause for the analgesic and anti-inflammatory action of the drug.
- Commonly used to relieve postoperative pain and morning stiffness.
- Has been shown to slow down pulmonary decline in cystic fibrosis sufferers.
- Chemical Formula: C13H18O2
- It is an NSAID.
Facts Source 2
Source 2 Title: Daily Med - Ibuprofen
MLA Citation: "IBUPROFEN - Ibuprofen tablet, Film Coated ." DailyMed. U.S. National Library of Medicine, Mar. 2010. Web.
- Ibuprofen Tablets, USP contain the active ingredient ibuprofen, which is (±) – 2 – (p – isobutylphenyl) propionic acid.
- Ibuprofen Tablets, USP, a nonsteroidal anti-inflammatory drug (NSAID).
- Available in 400 mg, 600 mg, and 800 mg tablets for oral administration.
- Its mode of action, like that of other NSAIDs, is not completely understood, but may be related to prostaglandin synthetase inhibition.
- The ibuprofen in ibuprofen tablets is rapidly absorbed.
- Peak serum ibuprofen levels are generally attained one to two hours after administration.
- Ibuprofen Tablets, USP are indicated for relief of the signs and symptoms of rheumatoid arthritis and osteoarthritis.
- Ibuprofen Tablets, USP are indicated for relief of mild to moderate pain.
- Ibuprofen Tablets, USP are also indicated for the treatment of primary dysmenorrhea.
- NSAIDs cause an increased risk of serious gastrointestinal adverse events including bleeding, ulceration, and perforation of the stomach or intestines, which can be fatal.
- Controlled studies have demonstrated that ibuprofen tablets are a more effective analgesic than propoxyphene.
- Relief of episiotomy pain, pain following dental extraction procedures, and for the relief of the symptoms of primary dysmenorrhea.